The project NANO-CATHEDRAL aims at developing new materials, technologies and procedures for the conservation of deteriorated stones in monumental buildings and cathedrals and high value contemporary architecture, with a particular emphasis on the preservation of the originality of materials and on the development of a tailor-made approach to tackle the specific problems related to the different lithotypes. In fact the objective is providing “key tools” in terms of innovative nano-structured conservation materials, for restoration and conservation on a full European scale, thanks to the research work made onto lithotypes representative of different European geographical areas and styles and of different climate and environmental conditions.